EPs 7630, a Herbal Drug Preparation for Treating Acute Bronchitis in Children and Adults
نویسنده
چکیده
Herbal medicines play an increasingly important role in the perception of physicians and patients looking for equally effective, albeit safer approaches to conventional management of acute bronchitis. A no antibiotic or delayed antibiotic prescribing strategy to reduce the inappropriate prescribing of antibiotics for respiratory tract infections (RTI) has been advocated since the late 1990’s (Little, 2005). In the light of inappropriate antibiotic use in this indication especially in children and increasing drug resistance rates worldwide, the need for an alternative remedy is crucial (Abbas et al., 2010). There is encouraging evidence derived from high quality randomised clinical trials (RCTs) that EPs 76301, a herbal drug preparation from the roots of Pelargonium sidoides widely used in several countries for the treatment of RTIs in children (≥1 year of age) and adults, is effective in patients with acute bronchitis.
منابع مشابه
Efficacy and tolerability of EPs 7630 in patients (aged 6–18 years old) with acute bronchitis
AIM For EPs-7630, a herbal drug preparation from Pelargonium sidoides roots, therapeutic effects in respiratory tract infections outside the strict indication for antibiotics have already been demonstrated in adults. Now, a dose-finding study for EPs-7630 was performed in children and adolescents. METHODS A total of 400 patients (aged 6-18 years) were randomized to receive either 30 mg, 60 mg...
متن کاملPelargonium sidoides extract EPs 7630: a review of its clinical efficacy and safety for treating acute respiratory tract infections in children
Background In numerous randomized controlled trials (RCTs) and systematic reviews such as those published by the Cochrane Collaboration, Pelargonium sidoides extract EPs® 7630 was shown to be effective in acute respiratory tract infections (aRTI) in all investigated age-groups. This narrative review focuses on recently published results from RCTs investigating the clinical efficacy and safety o...
متن کاملEPs 7630 in Acute Respiratory Tract Infections –Asystematic Review and Meta-Analysis of Randomized Clinical Trials
Submit Manuscript | http://medcraveonline.com Abbreviations: AB: Acute Bronchitis; AE: Adverse Event; ARS: Acute Rhinosinusitis; ATP: Acute Tonsillopharyngitis; BSS: Bronchitis Severity Scale; CI: Confidence Interval; IMOS: Integrative Medicine Outcome Scale; ISRCTN: International Standard Randomized Controlled Trial Number; MEDLINE: Medical Literature Analysis and Retrieval System Online; RTI:...
متن کاملAntimicrobial, Antiviral and Immunomodulatory Activity Studies of Pelargonium sidoides (EPs® 7630) in the Context of Health Promotion
Pelargonium species contribute significantly to the health care of a large population in the Southern African region, as part of a long-standing medical system intimately linked to traditional healing practices. Most notably, extracts of the roots of P. sidoides have commonly been applied for the treatment of dysentery and diarrhoea but only occasionally for respiratory complaints. Clinical tri...
متن کاملThe Pelargonium sidoides Extract EPs 7630 Drives the Innate Immune Defense by Activating Selected MAP Kinase Pathways in Human Monocytes
Pelargonium sidoides is a medical herb and respective extracts are used very frequently for the treatment of respiratory tract infections. However, the effects of Pelargonium sidoides and a special extract prepared from its roots (EPs 7630) on human immune cells are not fully understood. Here we demonstrate that EPs 7630 induced a rapid and dose-dependent production of TNF-α, IL-6, and IL-10 by...
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